Pyzina (Pyrazinamide)

Active Ingredient: Pyrazinamide
Dosage Form: Tablet
Available Strength: 500mg, 750mg
Manufacturer: Lupin Limited
Packaging: 10 Tablets in Strip
Therapeutic Use: Tuberculosis (TB)
Pack Insert/Leaflet: Yes
Production Capacity: 1 Million Tablet's/Month


Pyzina is a trusted medicine, manufactured by Lupin Limited which is a leading pharmaceutical company aimed at delivering effective treatment for combating TB successfully and regaining the health of millions of patients across the USA.

What is Pyzina?

Pyzina is the tablet name for the medicine Pyrazinamide. It is an antibiotic medication that plays a crucial role in the management of tuberculosis. These pills, which the WHO recommends, can be used to treat TB patients who are both drug-sensitive and drug-resistant.

Buy Pyzina Online USA

Being one of the widely used medicines for addressing TB infection you can easily get hold of the tablets from local and online pharmacies like In terms of online pharmacies when you make Pyzina online orders make sure you look for authentication and then only buy Pyzina online.

What is Pyzina Used for?

The Pyzina tablets are used to treat tuberculosis in combination with other first-line anti-tuberculosis medicines. This combination therapy allows you to shorten the duration of your treatment and reduce the overall risk of treatment.

How Does It Work?

The tablets are made of the active ingredient Pyrazinamide which is a standard regimen used to treat tuberculosis (TB). How it works is basically by destroying the synthesis of mycolic acid which is a key component of the cell wall of Mycobacterium tuberculosis. This acid is responsible for maintaining the structure of the bacterial cell wall and for its survival and growth as well.

The Pyzina tablet weakens the cell wall of the bacteria and actively works against slowing down bacterial growth.

How to take it?

These tablets are usually taken orally but there’s a standard method of taking the medicine. Here’s how you should take the tablets:

  1. Follow the prescribed dosage and duration of taking the tablet.
  2. Take one time daily, usually in the morning.
  3. Take it with food to avoid any kind of stomach upset.
  4. Swallow the tablets whole without crushing or chewing.

Additionally, you must complete your treatment even if you seem to have better results.

When not to use?

Even though it is a widely used medicine for TB there are certain situations under which you should not use the tablets. Here’s when you should not use the tablet if you have:

  1. Hypersensitivity
  2. Severe liver disease
  3. Gout
  4. Pregnancy and breastfeeding

Moreover, you should know what other medical issues you have for ensuring a mindful use of the tablets.


Dosage is one of the most important aspects of the treatment journey. While the usual dosage of the medicine is 15 to 30 mg/kg of your body weight at maximum. This holds true for kids and adults alike. But the dosages will need to be changed based on your medical conditions.

Missed Dose

A missed dose can be compensated with another as soon as you remember and avoid doubling up the dosage.


 Overdose has symptoms like nausea, vomiting, abdominal pain, and liver toxicity which needs immediate medical attention.


While there are multiple medicines for addressing TB infections, why should you take into consideration this particular medicine, what are its benefits?

  1. Helps rapidly reduce bacterial activity.
  2. Shorten the treatment duration of TB.
  3. Can be used alongside first-line anti-TB medicines as a combination therapy.
  4. Reduce transmission.
  5. Reduce the severity of symptoms.

Overall, upon accessing the Pyzina reviews we can say that these tablets are quite effective and reduce the infection.

Pyrazinamide Side Effects

The medicine does have some minimal side effects that you might experience while treating the infection. Such side effects are:

  • Gastrointestinal distress
  • Liver toxicity
  • Joint pain
  • Hyperuricemia
  • Allergic reaction
  • Changes in blood cell count

In case you find any of these side effects reflecting, consult medical help immediately.

Precautions And Warnings

While using these tablets for treating TB, there are a few precautionary factors you must count. Here’s what all you need to be warned of:

  • The active ingredient can damage the liver.
  • Be cautious of an increase in uric acid levels in your blood.
  • Diabetes patients should use it only after consultation.

We must warn you of the complications you need to be cautious about upon using the tablets.

Storage & Disposal

As important as knowing the properties of a medicine, it is equally important to know the proper storage and disposal methods of the tablets.

Storage- The tablets are meant to be stored at room temperature ideally away from both moisture and heat in their original packing.

Disposal- Dispose of expired and unused tablets as per the guidelines of medication disposal to prevent any kind of accidental ingestion.

Appropriate storage and disposal are essential for an overall sensible usage of the medicine.


Interaction amongst drugs must be evaluated well when you are adapting to medicine for treating TB infection for safe usage. Here’s what other medicines Pyrazinamide can interact with that you need to be aware of:

  • Allopurinol
  • Antacids
  • Isoniazid
  • Rifampin
  • Ethambutol
  • Warfarin
  • Diabetes medications

Hence, always make sure to go through your medical history to avoid any kind of interactions.


Pyrazinamide medicine has various strengths, which are prescribed depending on the specific needs of the TB treatment along with additional factors such as your weight and age. Depending on the same, here are two strengths of the medicine:

The 750 mg of Pyzina is prescribed at the initial stages, both pulmonary and extrapulmonary of tuberculosis treatment alongside a few first-line TB medicines like isoniazid and ethambutol. The 750mg strength is sufficient for inhibiting the active multiplication of TB bacteria and shortening the duration of treatment.

Apart from that, it is prescribed only to patients weighing more than 50 kg.

  • Pyzina 500 mg

500mg of the tablet can be prescribed to both adults and children for addressing the treatment of TB which is caused by Mycobacterium tuberculosis. Similar to the 750mg, even 500mg of the medicine is prescribed for patients over 50 kg.

The strength of the medicine plays an important role in the treatment of TB as it can cater to the specific levels of the infection and optimize combating tuberculosis infection treatment.

Safety Advice

Whenever you are on a medical treatment the concerns go beyond dosage, strength, and looking into the side effects. Moving ahead with a summarized safety guideline is an elevated step while you are taking the medicine for treating tuberculosis. Here’s all the safety advice you would require:

  • Take the prescribed dosage
  • Consume with food and not on an empty stomach
  • Drink enough water to avoid kidney stones
  • Undergo periodic liver function tests to monitor any signs of liver damage

Knowing about the safety measures will allow you to take charge of your health and move with your treatment responsibly.


In conclusion, Pyzina tablets are a comprehensive and trusted medicine for treating tuberculosis. The high-quality formulation and reliable efficacy make the tablets essential amongst patients and healthcare providers. The tablets stand as a beacon of hope for a world free of TB, offering you an effective path toward complete wellness.

Frequently Asked Questions

Can I take a Pyzina Tablet with food?

Yes, it is recommended to take the medicine with food and avoid taking the tablets on an empty stomach. Apart from that follow the administration instructions you have been given by your doctor upon assessing your health.

Can Pyrazinamide be used in children?

Yes, you can use the medicine to address tuberculosis issues among children. Having said that, when used amongst children the dosages and the duration of treatment are altered as per the child’s health.

Who should not take this tablet?

You should avoid Pyzina tablets if the active ingredient Pyrazinamide leads you to have side effects. Along with that, a tuberculosis patient with severe liver disease or a history of gout should not take this tablet unless you are prescribed the same by a doctor.

Can you consume alcohol while taking this tablet?

No, you should not consume alcohol while you are on tuberculosis treatment with Pyrazinamide. This is because alcohol results in increasing the risk of liver damage when interacting with Pyrazinamide. Hence evaluate all the possibilities of alcohol interaction before starting the tablets.


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